Dr. Christian Schulte

Christian Schulte

Christian is a PhD student in the Cardiovascular Division at King’s College London.

 

Education


2009-2013 “Results after aortic valve sparing replacement of the ascending aorta in the technique of David”
Grade: “magna cum laude”
University Heart Centre Hamburg Eppendorf, Germany
2017- PhD student, Cardiovascular Division
King’s College London, UK

 

Medical Qualification


2012- Resident Physician
at Department for General and Interventional Cardiology
University Heart Centre Hamburg Eppendorf, Germany

 

Basic Research Activities


2010 Optimization of Engineered Heart Tissue (EHT),
Department of Clinical Pharmacology and Toxicology,
UKE Hamburg Eppendorf, Germany
2012- Biomarker and microRNA analyses in cardiovascular disease
Department of Genomics and Systems Biology,
University Heart Centre Hamburg Eppendorf, Germany
2013- Member of the working group “microRNA”
of the ‘BiomarCaRE’ Consortium

 

Clinical Research Activities


2014-2016 Impella® on top of extracorporeal membrane oxygenation (ECMO) in patients with fulminant cardiogenic shock
2013- Observational Study on Contrast Media Induced Nephropathy

 

Publications


1 Schulte C, Singh B, Theofilatos K, Sörensen NA, Lehmacher J, Hartikainen T, Haller PM, Westermann D, Zeller T, Blankenberg S, Neumann JT, Mayr M . Serial measurements of protein and microRNA biomarkers to specify myocardial infarction subtypes. Journal of molecular and cellular cardiology plus. 2022 1 : 100014. [Full Text] [PubMed] [DOI]

2 Schulte C, Barwari T, Joshi A, Zeller T, Mayr M.. Noncoding RNAs versus protein biomarkers in cardiovascular disease. Trends in Molecular Medicine. 2020 26(6) : 583-596. [Full Text] [PubMed] [DOI]

3 Parker WAE, Schulte C, Barwari T, Phoenix F, Pearson SM, Mayr M, Grant PJ, Storey RF, Ajjan RA. Aspirin, clopidogrel and prasugrel monotherapy in patients with type 2 diabetes mellitus: a double-blind randomised controlled trial of the effects on thrombotic markers and microRNA levels.. Cardiovasc Diabetol. 2020 19(1) : 3. [Full Text] [PubMed] [DOI]

4 Schulte C, Joshi A, Mayr M.. Response by Schulte et al to Letter Regarding Article, Comparative Analysis of Circulating Noncoding RNAs Versus Protein Biomarkers in the Detection of Myocardial Injury. Circ Res.. 2019 125(4) : e22-e23. [Full Text] [PubMed] [DOI]

5 Schulte C, Barwari T, Joshi A, Theofilatos K, Zampetaki A, Barallobre-Barreiro J, Singh B, Sorensen N, Neumann JT, Zeller T, Westermann D.. Comparative Analysis of Circulating Non-Coding RNAs Versus Protein Biomarkers in the Detection of Myocardial Injury. Circulation research. 2019 Epub : . [Full Text] [PubMed] [DOI]

6 Schulte C, Mayr M. MicroRNAs: A New Understanding of Platelet Physiology and Pathology. Thromb Haemost. 2019 119 : 191. [Full Text] [PubMed] [DOI]

7 Barwari T, Eminaga S, Mayr U, Lu R, Armstrong PC, Chan MV, Sahraei M, Fernández-Fuertes M, Moreau T, Barallobre-Barreiro J, Lynch M, Yin X, Schulte C, Baig F, Pechlaner R, Langley SR, Zampetaki A, Santer P, Weger M, Plasenzotti R, Schosserer M, Grillari J, Kiechl S, Willeit J, Shah AM, Ghevaert C, Warner TD, Fernández-Hernando C, Suárez Y, Mayr M. Inhibition of profibrotic microRNA-21 affects platelets and their releasate. JCI Insight. 2018 3 : e123335. [Full Text] [PubMed] [DOI]

8 Pappalardo F, Schulte C, Pieri M, Schrage B, Contri R, Soeffker G, Greco T, Lembo R, Müllerleile K, Colombo A, Sydow K, De Bonis M, Wagner F, Reichenspurner H, Blankenberg S, Zangrillo A, Westermann D. Concomitant implantation of Impella® on top of veno-arterial extracorporeal membrane oxygenation may improve survival of patients with cardiogenic shock. Eur J Heart Fail. 2017 19 : 404-412. [PubMed] [DOI]

9 Schulte C, Karakas M, Zeller T. microRNAs in cardiovascular disease - clinical application. Clin Chem Lab Med. 2016 55 : 687-704. [Full Text] [PubMed] [DOI]

10 Karakas M, Schulte C, Appelbaum S, Ojeda F, Lackner KJ, Münzel T, Schnabel RB, Blankenberg S, Zeller T. Circulating microRNAs strongly predict cardiovascular death in patients with coronary artery disease-results from the large AtheroGene study. Eur Heart J. 2016 38 : 516-523. [PubMed] [DOI]

11 Schulte C, Westermann D, Blankenberg S, and Zeller T. Diagnostic and prognostic value of circulating microRNAs in heart failure with preserved and reduced ejection fraction. World J Cardiol. 2015 12 : 843-860. [Full Text] [PubMed] [DOI]

12 Schulte C, Molz S, Appelbaum S, Karakas M, Ojeda F, Lau DM, Hartmann T, Lackner KJ, Westermann D,Schnabel RB, Blankenberg S, Zeller T. miRNA-197 and miRNA-223 Predict Cardiovascular Death in a Cohort of Patients with Symptomatic Coronary Artery Disease. PLoS One. 2015 10 : e0145930. [Full Text] [PubMed] [DOI]

13 Schulte C, Zeller T. microRNA-based diagnostics and therapy in cardiovascular disease-Summing up the facts. Cardiovasc Diagn Ther. 2015 1 : 17-36. [Full Text] [PubMed] [DOI]

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